Proximal tubular angiotensin II levels and renal functional responses to AT1 receptor blockade in nonclipped kidneys of Goldblatt hypertensive rats.

@article{Cervenka1999ProximalTA,
  title={Proximal tubular angiotensin II levels and renal functional responses to AT1 receptor blockade in nonclipped kidneys of Goldblatt hypertensive rats.},
  author={Ludĕk C̆ervenka and Chung Tseng Wang and Kenneth David Mitchell and Luis Gabriel Navar},
  journal={Hypertension},
  year={1999},
  volume={33 1},
  pages={
          102-7
        }
}
-Previous studies have shown that whereas the nonclipped kidney in two-kidney, one clip (2K1C) rats undergoes marked depletion of renin content and renin mRNA, intrarenal angiotensin II (Ang II) levels are not suppressed; however, the distribution and functional consequences of intrarenal Ang II remain unclear. The present study was performed to assess the plasma, kidney, and proximal tubular fluid levels of Ang II and the renal responses to intrarenal Ang II blockade in the nonclipped kidneys… CONTINUE READING

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References

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Angiotensin type I receptor antagonist CV-11974 and EXP 3174 cause a selective renal vasodilatation in conscious spontaneously hypertensive rats

CL Xiao, RE Widdop
  • Clin Sci
  • 1996