Proximal location of mouse prostate epithelial stem cells

@article{Tsujimura2002ProximalLO,
  title={Proximal location of mouse prostate epithelial stem cells},
  author={A. Tsujimura and Y. Koikawa and S. Salm and T. Takao and S. Coetzee and D. Moscatelli and E. Shapiro and H. Lepor and T. Sun and E. Wilson},
  journal={The Journal of Cell Biology},
  year={2002},
  volume={157},
  pages={1257 - 1265}
}
  • A. Tsujimura, Y. Koikawa, +7 authors E. Wilson
  • Published 2002
  • Biology, Medicine
  • The Journal of Cell Biology
    • Stem cells are believed to regulate normal prostatic homeostasis and to play a role in the etiology of prostate cancer and benign prostatic hyperplasia. We show here that the proximal region of mouse prostatic ducts is enriched in a subpopulation of epithelial cells that exhibit three important attributes of epithelial stem cells: they are slow cycling, possess a high in vitro proliferative potential, and can reconstitute highly branched glandular ductal structures in collagen gels. We propose… CONTINUE READING
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    References

    SHOWING 1-10 OF 77 REFERENCES
    Prostatic ductal system in rats: Regional variation in stromal organization
    • 95
    Differentiation pathways and histogenetic aspects of normal and abnormal prostatic growth: A stem cell model
    • 409
    Stem cell features of benign and malignant prostate epithelial cells.
    • 235
    Ductal heterogeneity of cytokeratins, gene expression, and cell death in the rat ventral prostate.
    • 105
    • Highly Influential
    • PDF
    Evidence of stem cells in the adult prostatic epithelium based upon responsiveness to mesenchymal inductors
    • 46
    Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: Implications on epithelial stem cells
    • 1,274
    • PDF
    Prostatic ductal system in rats: Tissue‐specific expression and regional variation in stromal distribution of transforming growth factor‐β1
    • 58
    • Highly Influential
    Transforming growth factor-beta in benign and malignant prostate.
    • 45
    Prostatic ductal system in rats: regional variation in localization of an androgen-repressed gene product, sulfated glycoprotein-2.
    • 99
    The proliferative function of basal cells in the normal and hyperplastic human prostate
    • 248