Proximal colorectal dysplasia or cancer in ulcerative colitis. The impact of primary sclerosing cholangitis and sulfasalazine

@article{Lindberg2001ProximalCD,
  title={Proximal colorectal dysplasia or cancer in ulcerative colitis. The impact of primary sclerosing cholangitis and sulfasalazine},
  author={Briana Lindberg and Ulrika Broom{\'e} and Brittany Persson},
  journal={Diseases of the Colon & Rectum},
  year={2001},
  volume={44},
  pages={77-83}
}
PURPOSE: Known risk factors for the development of colorectal dysplasia or cancer in ulcerative colitis are total colonic involvement and long duration of the disease. It has recently been suggested that presence of primary sclerosing cholangitis is another independent risk factor—especially for proximal colorectal dysplasia or cancer—and that treatment with sulfasalazine might reduce the frequency of colorectal cancer in ulcerative colitis; the present study was undertaken to shed light on the… CONTINUE READING

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