Provocative tests with psychostimulant drugs in schizophrenia

@article{Lieberman2004ProvocativeTW,
  title={Provocative tests with psychostimulant drugs in schizophrenia},
  author={Jeffrey A. Lieberman and John M. Kane and Jose Ma. J. Alvir},
  journal={Psychopharmacology},
  year={2004},
  volume={91},
  pages={415-433}
}
The psychotogenic effects of psychostimulant drugs have provided a major line of evidence in support of the DA hypothesis of schizophrenia. To evaluate the effects of psychostimulant (PS) drugs inschizophrenia and the clinical variables which may influence their expression, we reviewed 36 studies of PS drugs in patients with schizophrenia. Approximately 40% evidence a psychotogenic response to PS administration in doses that are subpsychotogenic in normals. Specific clinical variables appear to… 

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