Provisional matrix: A role for versican and hyaluronan.

@article{Wight2017ProvisionalMA,
  title={Provisional matrix: A role for versican and hyaluronan.},
  author={Thomas N Wight},
  journal={Matrix biology : journal of the International Society for Matrix Biology},
  year={2017},
  volume={60-61},
  pages={
          38-56
        }
}
Hyaluronan and versican are extracellular matrix (ECM) components that are enriched in the provisional matrices that form during the early stages of development and disease. These two molecules interact to create pericellular "coats" and "open space" that facilitate cell sorting, proliferation, migration, and survival. Such complexes also impact the recruitment of leukocytes during development and in the early stages of disease. Once thought to be inert components of the ECM that help hold… CONTINUE READING

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