Provisional Mapping of Quantitative Trait Loci Modulating the Acoustic Startle Response and Prepulse Inhibition of Acoustic Startle

@article{Joober2002ProvisionalMO,
  title={Provisional Mapping of Quantitative Trait Loci Modulating the Acoustic Startle Response and Prepulse Inhibition of Acoustic Startle},
  author={Ridha Joober and Jean-Mary Zarate and Guy-Andr{\'e} Rouleau and Emil Skamene and Patricia Boksa},
  journal={Neuropsychopharmacology},
  year={2002},
  volume={27},
  pages={765-781}
}
Prepulse inhibition (PPI) of the acoustic startle response (ASR) is a form of sensorimotor gating, defined as an inhibition of the startle response when a low intensity stimulus, the prepulse, precedes the startling stimulus. Deficits in PPI have been reported in schizophrenia and other psychiatric/neurological disorders, and correlate with symptom severity in schizophrenia, suggesting that deficient PPI per se or abnormalities in neural circuits regulating PPI may cause some symptoms of… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 31 CITATIONS

Prepulse inhibition (PPI) of tactile startle response in recombinant congenic strains of mice: QTL mapping and comparison with acoustic PPI.

  • Journal of genetics and genomics = Yi chuan xue bao
  • 2008
VIEW 4 EXCERPTS
CITES RESULTS, METHODS & BACKGROUND
HIGHLY INFLUENCED

Identifying loci for behavioral traits using genome-tagged mice.

  • Journal of neuroscience research
  • 2003
VIEW 3 EXCERPTS
CITES RESULTS & BACKGROUND
HIGHLY INFLUENCED

Identification of quantitative trait loci for prepulse inhibition in rats

  • Psychopharmacology
  • 2002
VIEW 5 EXCERPTS
CITES BACKGROUND, RESULTS & METHODS
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 53 REFERENCES

Evaluation of biometrical methods for estimating the number of genes

  • Theoretical and Applied Genetics
  • 1985
VIEW 1 EXCERPT
HIGHLY INFLUENTIAL