Provirophages and transpovirons as the diverse mobilome of giant viruses

@article{Desnues2012ProvirophagesAT,
  title={Provirophages and transpovirons as the diverse mobilome of giant viruses},
  author={Christelle Desnues and Bernard La Scola and Natalya Yutin and Ghislain Fournous and Catherine Robert and Saı̈d Azza and Priscilla Jardot and Sonia Monteil and Ang{\'e}lique Campocasso and Eugene V. Koonin and Didier Raoult},
  journal={Proceedings of the National Academy of Sciences},
  year={2012},
  volume={109},
  pages={18078 - 18083}
}
A distinct class of infectious agents, the virophages that infect giant viruses of the Mimiviridae family, has been recently described. Here we report the simultaneous discovery of a giant virus of Acanthamoeba polyphaga (Lentille virus) that contains an integrated genome of a virophage (Sputnik 2), and a member of a previously unknown class of mobile genetic elements, the transpovirons. The transpovirons are linear DNA elements of ∼7 kb that encompass six to eight protein-coding genes, two of… 

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