Proviral load determination of different feline immunodeficiency virus isolates using real-time polymerase chain reaction: influence of mismatches on quantification.

@article{Klein1999ProviralLD,
  title={Proviral load determination of different feline immunodeficiency virus isolates using real-time polymerase chain reaction: influence of mismatches on quantification.},
  author={Dieter Klein and Philipp Janda and Ralf Steinborn and Manuela R. M{\"u}ller and Brian Salmons and Walter H. G{\"u}nzburg},
  journal={Electrophoresis},
  year={1999},
  volume={20 2},
  pages={291-9}
}
Lentiviruses are associated not only with immunodeficiency but also with malignancies. The mechanisms involved in tumorigenesis are still not fully understood. Cats infected with feline immunodeficiency virus (FIV) in the wild represent one model in which the role of viral load in the pathogenesis can be studied, since tumors, especially lymphomas, are quite often observed in cats infected with FIV. To be able to compare the viral load data among cats infected with different FIV isolates, the… CONTINUE READING