Providing patients with pharmacogenetic test results affects adherence to statin therapy: results of the Additional KIF6 Risk Offers Better Adherence to Statins (AKROBATS) trial

@article{Charland2014ProvidingPW,
  title={Providing patients with pharmacogenetic test results affects adherence to statin therapy: results of the Additional KIF6 Risk Offers Better Adherence to Statins (AKROBATS) trial},
  author={Scott L. Charland and Barnabie C Agatep and Vivian Herrera and Bettina Schrader and Felix W. Frueh and Michael Ryvkin and Junard Shabbeer and James J. Devlin and Harold Robert Superko and Eric J. Stanek},
  journal={The Pharmacogenomics Journal},
  year={2014},
  volume={14},
  pages={272-280}
}
Despite the clinical benefit of statin therapy and the numerous strategies used to improve adherence, no strategy has used direct communication of genetic test results to the patient as an adherence and persistence motivator. We investigated in a real-world setting the effect of a process of providing KIF6 test results and risk information directly to 647 tested patients on 6-month statin adherence (proportion of days covered (PDC)) and persistence compared with concurrent non-tested matched… CONTINUE READING
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