Prourokinase versus urokinase for recanalization of peripheral occlusions, safety and efficacy: the PURPOSE trial.

@article{Ouriel1999ProurokinaseVU,
  title={Prourokinase versus urokinase for recanalization of peripheral occlusions, safety and efficacy: the PURPOSE trial.},
  author={Kenneth Ouriel and Krishna Kandarpa and Debra M Schuerr and Micki Hultquist and G Hodkinson and Bruce Wallin},
  journal={Journal of vascular and interventional radiology : JVIR},
  year={1999},
  volume={10 8},
  pages={1083-91}
}
BACKGROUND The intraarterial administration of thrombolytic agents is associated with clinical benefits in patients with acute peripheral arterial occlusion, and urokinase has been the agent that has become the standard of care in the United States. Recombinant prourokinase (r-ProUK) offers potential as a novel agent with improved fibrin specificity and, as… CONTINUE READING