Proultraflexible lipid vesicles for effective transdermal delivery of levonorgestrel: Development, characterization, and performance evaluation

@article{Jain2005ProultraflexibleLV,
  title={Proultraflexible lipid vesicles for effective transdermal delivery of levonorgestrel: Development, characterization, and performance evaluation},
  author={Subheet Jain and Rachna Sapre and Ashok K Tiwary and Narendra Kumar Jain},
  journal={AAPS PharmSciTech},
  year={2005},
  volume={6},
  pages={E513-E522}
}
The present investigation aimed at formulation, performance evaluation, and stability studies of new vesicular drug carrier system protransfersomes for transdermal delivery of the contraceptive agent, levonorgestrel. Protransfersome gel (PTG) formulations of levonorgestrel were prepared and characterized for vesicle shape, size, entrapment efficiency, turbidity, and drug permeation across rat skin and were evaluated for their stability. The system was evaluated in vivo for biological assay of… CONTINUE READING

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