Protracted withdrawal from alcohol and drugs of abuse impairs long-term potentiation of intrinsic excitability in the juxtacapsular bed nucleus of the stria terminalis.

@article{Francesconi2009ProtractedWF,
  title={Protracted withdrawal from alcohol and drugs of abuse impairs long-term potentiation of intrinsic excitability in the juxtacapsular bed nucleus of the stria terminalis.},
  author={Walter Francesconi and Fulvia Berton and Vez Repunte-Canonigo and Kazuki Hagihara and David Thurbon and Dusan M Lekic and Sheila E. Specio and Thomas N. Greenwell and Scott Chen and Kenner C. Rice and Heather N Richardson and Laura E O'Dell and Eric Zorrilla and Marisela Morales and George F. Koob and Pietro Paolo Sanna},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2009},
  volume={29 17},
  pages={5389-401}
}
The juxtacapsular bed nucleus of the stria terminalis (jcBNST) is activated in response to basolateral amygdala (BLA) inputs through the stria terminalis and projects back to the anterior BLA and to the central nucleus of the amygdala. Here we show a form of long-term potentiation of the intrinsic excitability (LTP-IE) of jcBNST neurons in response to high-frequency stimulation of the stria terminalis. This LTP-IE, which was characterized by a decrease in the firing threshold and increased… CONTINUE READING