Protracted histopathological change of the liver necrosis induced by Shwartzman reaction. An experimental animal model of liver cirrhosis?

@article{Shiga1985ProtractedHC,
  title={Protracted histopathological change of the liver necrosis induced by Shwartzman reaction. An experimental animal model of liver cirrhosis?},
  author={Junji Shiga and Wataru Mori},
  journal={Acta pathologica japonica},
  year={1985},
  volume={35 1},
  pages={103-7}
}
Severe pathological fibrotic change of rabbits treated with endotoxin was produced. The liver of the rabbits that died within 14 days showed severe architectural distortion through wide fibrotic band which could be called morphologically post necrotic liver cirrhosis. On the other hand, in the liver of the rabbits that remained alive more than 14 days thin… CONTINUE READING