Protracted brain development in a rodent model of extreme longevity

  title={Protracted brain development in a rodent model of extreme longevity},
  author={Orsolya K. Penz and Janos Fuzik and Aleksandra B. Kurek and Roman A Romanov and John Larson and Thomas J Park and Tibor Harkany and Erik Keimpema},
  booktitle={Scientific reports},
Extreme longevity requires the continuous and large-scale adaptation of organ systems to delay senescence. Naked mole rats are the longest-living rodents, whose nervous system likely undergoes life-long adaptive reorganization. Nevertheless, neither the cellular organization of their cerebral cortex nor indices of structural neuronal plasticity along extreme time-scales have been established. We find that adult neurogenesis and neuronal migration are not unusual in naked mole rat brains… CONTINUE READING
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