Protracted administration of weekly docetaxel in metastatic breast cancer.

@article{Kuroi2003ProtractedAO,
  title={Protracted administration of weekly docetaxel in metastatic breast cancer.},
  author={Katsumasa Kuroi and Hiroko Bando and Shigehira Saji and Masakazu Toi},
  journal={Oncology reports},
  year={2003},
  volume={10 5},
  pages={1479-84}
}
The purpose of this study was to evaluate the efficacy and toxicity of weekly docetaxel in metastatic breast cancer. Fifty-seven patients were enrolled in this study of weekly docetaxel given at 25 mg/m(2)/week as a 1-h infusion in out-patient setting. Each cycle consisted of 3 weeks of therapy followed by 1-week treatment break, and the patients received a median of 24 infusions with a median cumulative dose of 600 mg/m(2). Overall response rate was 30% [95% confidence interval (CI), 18-42… CONTINUE READING