Prototype Nerve-Specific Near-Infrared Fluorophores
@article{Park2014PrototypeNN, title={Prototype Nerve-Specific Near-Infrared Fluorophores}, author={M. H. Park and Hoon Hyun and Yoshitomo Ashitate and H. Wada and G. Park and J. Lee and Costyl N Njiojob and M. Henary and J. V. Frangioni and H. Choi}, journal={Theranostics}, year={2014}, volume={4}, pages={823 - 833} }
Nerve preservation is an important issue during most surgery because accidental transection or injury results in significant morbidity, including numbness, pain, weakness, or paralysis. Currently, nerves are still identified only by gross appearance and anatomical location during surgery, without intraoperative image guidance. Near-infrared (NIR) fluorescent light, in the wavelength range of 650-900 nm, has the potential to provide high-resolution, high-sensitivity, and real-time avoidance of… CONTINUE READING
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