Protostane Triterpenoids from the Rhizome of Alisma orientale Exhibit Inhibitory Effects on Human Carboxylesterase 2.

@article{Mai2015ProtostaneTF,
  title={Protostane Triterpenoids from the Rhizome of Alisma orientale Exhibit Inhibitory Effects on Human Carboxylesterase 2.},
  author={Zhenpeng Mai and K. Zhou and Guangbo Ge and Chao Wang and Xiaokui Huo and Peipei Dong and Sa Deng and Bao-jing Zhang and Hou-li Zhang and Shan-shan Huang and X. Ma},
  journal={Journal of natural products},
  year={2015},
  volume={78 10},
  pages={
          2372-80
        }
}
Twelve new and 10 known protostane triterpenoids were isolated from the rhizome of Alisma orientale. Their structures were elucidated based on physical data analyses, including UV, HRESIMS, NMR experiments ((1)H, (13)C NMR, (1)H-(1)H COSY, HSQC, HMBC, and NOESY), and induced electronic circular dichroism. New compounds 1-12 were classified as protostanes (1-10), 29-norprotostane (11), and 24-norprotostane (12) by structure analyses. Furthermore, the inhibitory effects on human carboxylesterases… Expand
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