Protons extruded by NHE1: digestive or glue?

  title={Protons extruded by NHE1: digestive or glue?},
  author={Christian M. Stock and Rosa Angela Cardone and Giovanni Busco and Hermann Kraehling and Albrecht Schwab and Stephan Joel Reshkin},
  journal={European journal of cell biology},
  volume={87 8-9},
Many physiological and pathophysiological processes, such as embryogenesis, immune defense, wound healing, or metastasis, are based on cell migration and invasion. The activity of the ubiquitously expressed NHE1 isoform of the plasma membrane Na(+)/H(+) exchanger is one of the requirements for directed locomotion of migrating cells. The mechanisms by which NHE1 is involved in cell migration are multiple. NHE1 contributes to cell migration by affecting the cell volume, by regulating the… CONTINUE READING

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