Proton transfers in the bacteriorhodopsin photocycle.

  title={Proton transfers in the bacteriorhodopsin photocycle.},
  author={Janos K. Lanyi},
  journal={Biochimica et biophysica acta},
  volume={1757 8},
The steps in the mechanism of proton transport in bacteriorhodopsin include examples for most kinds of proton transfer reactions that might occur in a transmembrane pump: proton transfer via a bridging water molecule, coupled protonation/deprotonation of two buried groups separated by a considerable distance, long-range proton migration over a hydrogen-bonded aqueous chain, and capture as well as release of protons at the membrane-water interface. The conceptual and technical advantages of this… CONTINUE READING

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