Proton transfer reaction-mass spectrometry applications in medical research.

  title={Proton transfer reaction-mass spectrometry applications in medical research.},
  author={Jens Herbig and Anton Amann},
  journal={Journal of breath research},
  volume={3 2},
Gathering information about a subject's physiological and pathophysiological condition from the `smell' of breath is an idea that dates back to antiquity. This intriguing concept of non-invasive diagnosis has been revitalized by `exhaled breath analysis' in recent decades. A main driving force was the development of sensitive and versatile gas-chromatographic and mass-spectrometric instruments for trace gas analysis. Ironically, only non-smelling constituents of breath, such as O(2), CO(2), H(2… CONTINUE READING
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