Proton secretion in the male reproductive tract: involvement of Cl--independent HCO-3 transport.

@article{Breton1998ProtonSI,
  title={Proton secretion in the male reproductive tract: involvement of Cl--independent HCO-3 transport.},
  author={Sylvie Breton and K. M. Hammar and Pjs Smith and Dennis L. Brown},
  journal={The American journal of physiology},
  year={1998},
  volume={275 4 Pt 1},
  pages={C1134-42}
}
The lumen of the epididymis is the site where spermatozoa undergo their final maturation and acquire the capacity to become motile. An acidic luminal fluid is required for the maintenance of sperm quiescence and for the prevention of premature activation of acrosomal enzymes during their storage in the cauda epididymis and vas deferens. We have previously demonstrated that a vacuolar H+-ATPase [proton pump (PP)] is present in the apical pole of apical and narrow cells in the caput epididymis… CONTINUE READING