Proton-pump inhibitors reduce the risk of uncomplicated peptic ulcer in elderly either acute or chronic users of aspirin/non-steroidal anti-inflammatory drugs.

@article{Pilotto2004ProtonpumpIR,
  title={Proton-pump inhibitors reduce the risk of uncomplicated peptic ulcer in elderly either acute or chronic users of aspirin/non-steroidal anti-inflammatory drugs.},
  author={Alberto Pilotto and Marilisa Franceschi and Gioacchino Leandro and Francesco Paris and Leandro Cascavilla and Maria Grazia Longo and Valeria Niro and Angelo Andriulli and Carlo Scarcelli and Francesco Di Mario},
  journal={Alimentary pharmacology & therapeutics},
  year={2004},
  volume={20 10},
  pages={1091-7}
}
BACKGROUND Although administration of gastroprotective drugs may reduce the risk of peptic ulcers associated with the chronic use of non-steroidal anti-inflammatory drugs or aspirin, no consensus exists as to whether this co-therapy is effective for short-term prevention, particularly in old age. AIM To evaluate the risk of peptic ulcer associated with acute and chronic non-steroidal anti-inflammatory drugs or aspirin therapy in elderly subjects, and the influence of antisecretory treatment… CONTINUE READING
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