Proton pump inhibitors: better acid suppression when taken before a meal than without a meal

@article{Hatlebakk2000ProtonPI,
  title={Proton pump inhibitors: better acid suppression when taken before a meal than without a meal},
  author={Jan Gunnar Hatlebakk and P. O. Katz and Luciana Camacho-Lobato and Donald O. Castell},
  journal={Alimentary Pharmacology \& Therapeutics},
  year={2000},
  volume={14}
}
Proton pump inhibitors including omeprazole and lansoprazole inhibit gastric acid secretion by selectively and non‐competitively inactivating the H+, K+ ATPase molecules of the parietal cell, but possibly only those that are actively secreting acid. This might imply that stimulation of acid secretion by a meal is necessary for optimal inhibition of gastric secretion. 

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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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