Proton magnetic resonance spectroscopy of the primary motor cortex in patients with motor neuron disease: subgroup analysis and follow-up measurements.

@article{Block1998ProtonMR,
  title={Proton magnetic resonance spectroscopy of the primary motor cortex in patients with motor neuron disease: subgroup analysis and follow-up measurements.},
  author={Wolfgang Block and J Karitzky and F Tr{\"a}ber and Christoph Pohl and Ewald Keller and Rustam R. Mundegar and Rolf M. Lamerichs and Hermann Rink and Fernand Ries and Hans Heinz Schild and Felix Jerusalem},
  journal={Archives of neurology},
  year={1998},
  volume={55 7},
  pages={
          931-6
        }
}
OBJECTIVES To determine the motor cortex degeneration in patients with amyotrophic lateral sclerosis (ALS) using proton magnetic resonance spectroscopy, and to prove that proton magnetic resonance spectroscopy is suited to monitor the course of disease with follow-up examinations. MATERIALS AND METHODS We studied 33 patients with ALS whose conditions were diagnosed according to the El Escorial World Federation of Neurology criteria. Nine patients with ALS were followed up for up to 2 years… CONTINUE READING

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