Proton magnetic resonance spectroscopy as a probe into the pathophysiology of autism spectrum disorders (ASD): a review.

@article{Baruth2013ProtonMR,
  title={Proton magnetic resonance spectroscopy as a probe into the pathophysiology of autism spectrum disorders (ASD): a review.},
  author={Joshua M Baruth and Christopher A Wall and Marc C. Patterson and John D Port},
  journal={Autism research : official journal of the International Society for Autism Research},
  year={2013},
  volume={6 2},
  pages={119-33}
}
  • Joshua M Baruth, Christopher A Wall, +1 author John D Port
  • Published 2013 in
    Autism research : official journal of the…
  • DOI:10.1002/aur.1273
Proton magnetic resonance spectroscopy ((1) H-MRS) is a safe, noninvasive way of quantifying in vivo biochemical and metabolite concentration levels in individuals with Autism Spectrum Disorders (ASD). Findings to date suggest ASD is associated with widespread reduction in N-acetylaspartate (NAA), creatine plus phosphocreatine (Cr), choline-containing compounds (Cho), myo-inositol (mI), and glutamate plus glutamine plus gamma-Aminobutyric Acid (Glx); however, variable findings, and even… CONTINUE READING