Proton-induced sodium current in frog isolated dorsal root ganglion cells.

@article{Akaike1990ProtoninducedSC,
  title={Proton-induced sodium current in frog isolated dorsal root ganglion cells.},
  author={Norio Akaike and Oleg A. Krishtal and Takashi Maruyama},
  journal={Journal of neurophysiology},
  year={1990},
  volume={63 4},
  pages={
          805-13
        }
}
1. The proton-induced current was examined in isolated frog dorsal root ganglion (DRG) cells by the use of the "concentration-clamp" technique, which allows intracellular perfusion and rapid change of external solution with various pH (pHo) within 2 ms under single-electrode voltage-clamp condition. 2. Over one-half of the examined neurons showed no response for a "step" reduction of pHo even in a Ca2(+)-free external solution. In smaller neurons having a diameter less than 20 microns, the… CONTINUE READING

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