Proton Pump Inhibitors

@article{Richardson2012ProtonPI,
  title={Proton Pump Inhibitors},
  author={P. Richardson and C. Hawkey and W. A. Stack},
  journal={Drugs},
  year={2012},
  volume={56},
  pages={307-335}
}
  • P. Richardson, C. Hawkey, W. A. Stack
  • Published 2012
  • Medicine, Chemistry
  • Drugs
  • Proton pump inhibitors (PPIs) are drugs which irreversibly inhibit proton pump (H+/K+ ATPase) function and are the most potent gastric acid-suppressing agents in clinical use. There is now a substantial body of evidence showing improved efficacy of PPIs over the histamine H2 receptor antagonists and other drugs in acid-related disorders.Omeprazole 20 mg/day, lansoprazole 30 mg/day, pantoprazole 40 mg/day or rabeprazole 20 mg/day for 2 to 4 weeks are more effective than standard doses of H2… CONTINUE READING

    Paper Mentions

    A review of proton-pump inhibitors
    1
    Chapter 4 – Omeprazole

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 261 REFERENCES
    Omeprazole. An update of its pharmacology and therapeutic use in acid-related disorders.
    158
    The chemotherapeutic effects of H+/K+ inhibitors on Helicobacter pylori infection.
    9
    Profound Gastric Acid Inhibition: Advantages and Potential Hazards
    10
    Helicobacter pylori urease inhibition by rabeprazole, a proton pump inhibitor.
    59
    A trial of lansoprazole in refractory gastric ulcer.
    7
    Famotidine for the prevention of gastric and duodenal ulcers caused by nonsteroidal antiinflammatory drugs.
    415