Proton MR spectroscopy in mild cognitive impairment and Alzheimer disease: comparison of 1.5 and 3 T.

@article{Kantarci2003ProtonMS,
  title={Proton MR spectroscopy in mild cognitive impairment and Alzheimer disease: comparison of 1.5 and 3 T.},
  author={Kejal Kantarci and Glenn Reynolds and Ronald C. Petersen and Bradley F. Boeve and David S. Knopman and Steven Edland and Glenn E. Smith and Robert J. Ivnik and Eric G. Tangalos and Clifford R. Jack},
  journal={AJNR. American journal of neuroradiology},
  year={2003},
  volume={24 5},
  pages={843-9}
}
BACKGROUND AND PURPOSE Theoretically, proton ((1)H) MR spectroscopy at a higher field strength has the advantages of higher signal-to-noise ratio and improved spectral resolution. We therefore compared the ability of single-voxel (1)H MR spectroscopy at 1.5 and 3 T to diagnostically discriminate among cognitively normal elderly subjects, patients with mild cognitive impairment (MCI), and patients with Alzheimer disease (AD). METHODS At both 1.5 and 3 T, we studied 41 cognitively normal… CONTINUE READING
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