Proton MR Spectroscopy of Substantia Nigra in the Human Brain at 4 Tesla : Measurement of High GABA Concentrations

@inproceedings{Oz2002ProtonMS,
  title={Proton MR Spectroscopy of Substantia Nigra in the Human Brain at 4 Tesla : Measurement of High GABA Concentrations},
  author={G{\"u}lin Oz and Paul J. Tuite and Melissa Terpstra and Ivan Tkac and Pratibha G Aia and Jodi Lowary and Rolf Gruetter},
  year={2002}
}
Introduction Parkinson’s disease (PD) is characterized by loss of dopaminergic neurons in the substantia nigra (SN), but its etiology remains poorly understood (1). In vivo H MRS may provide a noninvasive alternative to culture, animal model and post-mortem studies that are more commonly utilized to understand the pathogenesis of PD. However, due to its… CONTINUE READING