Protocol for the fast chromatin immunoprecipitation (ChIP) method

  title={Protocol for the fast chromatin immunoprecipitation (ChIP) method},
  author={J. Nelson and O. Denisenko and K. Bomsztyk},
  journal={Nature Protocols},
  • J. Nelson, O. Denisenko, K. Bomsztyk
  • Published 2006
  • Medicine, Biology
  • Nature Protocols
  • Chromatin and transcriptional processes are among the most intensively studied fields of biology today. The introduction of chromatin immunoprecipitations (ChIP) represents a major advancement in this area. This powerful method allows researchers to probe specific protein-DNA interactions in vivo and to estimate the density of proteins at specific sites genome-wide. We have introduced several improvements to the traditional ChIP assay, which simplify the procedure, greatly reducing the time and… CONTINUE READING

    Figures and Topics from this paper.

    Explore Further: Topics Discussed in This Paper

    A rapid micro chromatin immunoprecipitation assay (ChIP)
    • 233
    • PDF
    Automated microfluidic chromatin immunoprecipitation from 2,000 cells.
    • 82
    • PDF
    μChIP—a rapid micro chromatin immunoprecipitation assay for small cell samples and biopsies
    • 83
    • Highly Influenced
    • PDF
    MicroChIP: chromatin immunoprecipitation for small cell numbers.
    • 34
    • Highly Influenced
    The Current State of Chromatin Immunoprecipitation
    • 225


    Publications referenced by this paper.
    Fast chromatin immunoprecipitation assay
    • 189
    • PDF
    Single-Nucleosome Mapping of Histone Modifications in S. cerevisiae
    • 505
    • PDF