Prothrombin gene polymorphism and coronary ischaemic syndromes : a phenotype-specific meta-analysis of 12 034 subjects

@inproceedings{Burzotta2003ProthrombinGP,
  title={Prothrombin gene polymorphism and coronary ischaemic syndromes : a phenotype-specific meta-analysis of 12 034 subjects},
  author={Francesco Burzotta and Katia Paciaroni and Valerio De Stefano and Filippo Crea and Attilio Maseri and Gianpiero Leone and Felicita Andreotti},
  year={2003}
}
Objective: To investigate the possible link between the G20210A prothrombin gene variant and different forms of ischaemic heart disease. Design: Phenotype-specific meta-analysis of 19 studies published within March 2002, globally including 4944 patients and 7090 controls. Sample size, inclusion criteria, geographical location, clinical presentation, age, cardiovascular risk factors, and angiographic extent of disease were extracted from each study. Analyses were done according to Mantel… CONTINUE READING