Prothrombin A19911G polymorphism and the risk of venous thromboembolism.

@article{Martinelli2006ProthrombinAP,
  title={Prothrombin A19911G polymorphism and the risk of venous thromboembolism.},
  author={Ida Martinelli and Tullia Battaglioli and Alberto Tosetto and Cristina Legnani and Lorenzo Sottile and Rossella Ghiotto and Pier Mannuccio Mannucci},
  journal={Journal of thrombosis and haemostasis : JTH},
  year={2006},
  volume={4 12},
  pages={
          2582-6
        }
}
BACKGROUND The A > G polymorphism at position 19911 of the prothrombin gene is associated with increased plasma prothrombin levels but its role as a risk factor for venous thromboembolism (VTE) is not established. OBJECTIVE To investigate the role of prothrombin 19911 A > G polymorphism in the risk of VTE in patients with heterozygous prothrombin 20210GA or factor (F) V Leiden and in those without thrombophilia. PATIENTS AND METHODS Case-control study of 793 patients with prothrombin 20210… CONTINUE READING
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