Proteomics of differential extraction fractions enriched for chromatin-binding proteins from colon adenoma and carcinoma tissues.

@article{Knol2014ProteomicsOD,
  title={Proteomics of differential extraction fractions enriched for chromatin-binding proteins from colon adenoma and carcinoma tissues.},
  author={Jaco C. Knol and Meike de Wit and Jakob Albrethsen and Sander R. Piersma and Thang V. Pham and Sandra Mongera and Beatriz Carvalho and Remond J A Fijneman and G A Meijer and Connie R. Jimenez},
  journal={Biochimica et biophysica acta},
  year={2014},
  volume={1844 5},
  pages={1034-43}
}
BACKGROUND Altered nuclear and genomic structure and function are hallmarks of cancer cells. Research into nuclear proteins in human tissues could uncover novel molecular processes in cancer. Here, we examine biochemical tissue fractions containing chromatin-binding (CB) proteins in the context of colorectal cancer (CRC) progression. METHODS CB protein-containing fractions were biochemically extracted from human colorectal tissues, including carcinomas with chromosomal instability (CIN… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
3 Extracted Citations
0 Extracted References
Similar Papers