Proteomics in gram-negative bacterial outer membrane vesicles.

  title={Proteomics in gram-negative bacterial outer membrane vesicles.},
  author={Eun-Young Lee and Dong-Sic Choi and Kwang-Pyo Kim and Yong Song Gho},
  journal={Mass spectrometry reviews},
  volume={27 6},
Gram-negative bacteria constitutively secrete outer membrane vesicles (OMVs) into the extracellular milieu. Recent research in this area has revealed that OMVs may act as intercellular communicasomes in polyspecies communities by enhancing bacterial survival and pathogenesis in hosts. However, the mechanisms of vesicle formation and the pathophysiological roles of OMVs have not been clearly defined. While it is obvious that mass spectrometry-based proteomics offers great opportunities for… CONTINUE READING


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