Proteomics Analysis Identifies New Components of the Fission and Budding Yeast Anaphase-Promoting Complexes

@article{Yoon2002ProteomicsAI,
  title={Proteomics Analysis Identifies New Components of the Fission and Budding Yeast Anaphase-Promoting Complexes},
  author={Hyun-Joo Yoon and Anna S Feoktistova and Benjamin A. Wolfe and Jennifer L. Jennings and Andrew J. Link and Kathleen L. Gould},
  journal={Current Biology},
  year={2002},
  volume={12},
  pages={2048-2054}
}
The anaphase-promoting complex (APC) is a conserved multisubunit ubiquitin ligase required for the degradation of key cell cycle regulators. Components of the APC have been identified through genetic screens in both Schizosaccharomyces pombe and Saccharomyces cerevisiae as well as through biochemical purification coupled with mass spectrometric protein… CONTINUE READING