Proteomic tools for the investigation of human hair structural proteins and evidence of weakness sites on hair keratin coil segments.

@article{Barthlemy2012ProteomicTF,
  title={Proteomic tools for the investigation of human hair structural proteins and evidence of weakness sites on hair keratin coil segments.},
  author={Nicolas R Barth{\'e}lemy and Audrey Bednarczyk and Christine Schaeffer-Reiss and Dominique Jullien and Alain van Dorsselaer and N{\"u}khet Cavusoglu},
  journal={Analytical biochemistry},
  year={2012},
  volume={421 1},
  pages={43-55}
}
Human hair is principally composed of hair keratins and keratin-associated proteins (KAPs) that form a complex network giving the hair its rigidity and mechanical properties. However, during their growth, hairs are subject to various treatments that can induce irreversible damage. For a better understanding of the human hair protein structures, proteomic mass spectrometry (MS)-based strategies could assist in characterizing numerous isoforms and posttranslational modifications of human hair… CONTINUE READING