Proteomic profiling of urine: implications for lupus nephritis.

  title={Proteomic profiling of urine: implications for lupus nephritis.},
  author={Najla Aljaberi and Michael Isaiah Bennett and Hermine I Brunner and Prasad Devarajan},
  journal={Expert review of proteomics},
INTRODUCTION Lupus nephritis (LN) is a common and significant manifestation, affecting 60% of adults and 80% of children with systemic lupus erythematosus, with up to 30% of patients progressing to end stage renal disease. There remains an unmet need for non-invasive markers of disease activity, damage, and response to therapy. In addition, non-invasive biomarkers that predict therapeutic efficacy are needed to enable cost-effective clinical trials of novel agents. Areas covered: This review… CONTINUE READING

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