Proteomic profiling of proteins in rat spinal cord induced by contusion injury.

@article{Yan2010ProteomicPO,
  title={Proteomic profiling of proteins in rat spinal cord induced by contusion injury.},
  author={Xiaodong Yan and Juanfang Liu and Zhanpeng Luo and Qinxue Ding and Xinggang Mao and Ming Yan and Shuguang Yang and Xueyu Hu and Jinghui Huang and Zhuojing Luo},
  journal={Neurochemistry international},
  year={2010},
  volume={56 8},
  pages={971-83}
}
It is widely accepted that mechanical injury to spinal cord can cause nervous system dysfunction, which leads to the loss of movement and sensation. However, the exact molecular mechanism is currently unclear. In this study, contused rat spinal cords were collected at 8h, 1 day, 3, and 5 days after injury and the expression patterns of the proteins were monitored and quantified with two-dimensional gel electrophoresis-based proteomics. Fifty-one protein spots showed significant regulation at… CONTINUE READING

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