Proteomic profiling of primary breast cancer predicts axillary lymph node metastasis.

  title={Proteomic profiling of primary breast cancer predicts axillary lymph node metastasis.},
  author={Taku Nakagawa and Sharon K S Huang and Steve R. Martinez and Andy N. Tran and David A. Elashoff and Xing Ye and Roderick R. Turner and Armando E. Giuliano and Dave S. B. Hoon},
  journal={Cancer research},
  volume={66 24},
To determine if protein expression in primary breast cancers can predict axillary lymph node (ALN) metastasis, we assessed differences in protein expression between primary breast cancers with and without ALN metastasis using surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS). Laser capture microdissection was performed on invasive breast cancer frozen sections from 65 patients undergoing resection with sentinel lymph node (SLN) or level I and II ALN… CONTINUE READING


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Cancer staging manual

  • FL Greene, DL Page, ID Fleming
  • 2002
Highly Influential
4 Excerpts

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