Proteomic profile of the hard corona of charged polystyrene nanoparticles exposed to sea urchin : Paracentrotus lividus coelomic fluid highlights potential drivers of toxicity

@article{Grassi2019ProteomicPO,
  title={Proteomic profile of the hard corona of charged polystyrene nanoparticles exposed to sea urchin : Paracentrotus lividus coelomic fluid highlights potential drivers of toxicity},
  author={Giacomo Grassi and Claudia Landi and Camilla Della Torre and Elisa Bergami and Luca Bini and Ilaria Corsi},
  journal={Environmental science. Nano},
  year={2019},
  volume={6},
  pages={2937-2947}
}
Polystyrene nanoparticles (PS NPs) are considered an upcoming threat to marine ecosystems. When NPs encounter biological fluids, they are readily covered by a biomolecular coating, named the “protein corona”, which critically drives the biological fate and toxicity of NPs. Here we provide the first attempt to identify key components of protein coronas of charged amino- and carboxyl-functionalized (PS-NH2 and PS-COOH, respectively) PS NPs exposed to coelomic fluid (CF) of the Mediterranean sea… Expand
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