Proteomic pleiotropy of OpgGH, an operon necessary for efficient growth of Salmonella enterica serovar typhimurium under low-osmotic conditions.

@article{Cooper2012ProteomicPO,
  title={Proteomic pleiotropy of OpgGH, an operon necessary for efficient growth of Salmonella enterica serovar typhimurium under low-osmotic conditions.},
  author={Bret Cooper and Ruiqiang Chen and Wesley M. Garrett and Charles Murphy and Caren Chang and Mark L Tucker and Arvind A. Bhagwat},
  journal={Journal of proteome research},
  year={2012},
  volume={11 3},
  pages={
          1720-7
        }
}
Salmonella enterica, a bacterial, food-borne pathogen of humans, can contaminate raw fruits and vegetables. Unfortunately for consumers, the bacteria can survive in water used to wash away contaminating bacteria. The ability to survive the low-osmotic conditions of the wash water is attributed to the OpgGH operon that leads to the production of osmotically regulated periplasmic glucans. Mutants lacking OpgGH grow slowly under low-osmotic conditions, but there are also unexpected traits such as… CONTINUE READING
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