Proteomic methods reveal cyclophilin A function as a host restriction factor against rotavirus infection.

Abstract

Rotavirus (RV) infection is the main cause of acute dehydrating diarrhea in infants and young children below 5 years old worldwide. RV infection causes a global shutoff of host proteins as many other viruses do. However, previous studies revealed that RV could selectively upregulated the expression of some host proteins that then played important roles in… (More)
DOI: 10.1002/pmic.201100579

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