Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71.

Abstract

Alzheimer's disease (AD) is a neurodegenerative disorder in which oxidative stress has been implicated as an important event in the progression of the pathology. In particular, it has been shown that protein modification by reactive oxygen species (ROS) occurs to a greater extent in AD than in control brain, suggesting a possible role for oxidation-related… (More)

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@article{Castegna2002ProteomicIO, title={Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71.}, author={Alessandra Castegna and Michael Y. Aksenov and Visith Thongboonkerd and Jon B. Klein and William M. Pierce and Rosemarie M Booze and William R. Markesbery and D. Butterfield}, journal={Journal of neurochemistry}, year={2002}, volume={82 6}, pages={1524-32} }