Proteomic characterization of human proinflammatory M1 and anti-inflammatory M2 macrophages and their response to Candida albicans.

@article{RealesCaldern2014ProteomicCO,
  title={Proteomic characterization of human proinflammatory M1 and anti-inflammatory M2 macrophages and their response to Candida albicans.},
  author={Jose Antonio Reales-Calder{\'o}n and Noem{\'i} Aguilera-Montilla and {\'A}ngel L Corb{\'i} and Gloria Molero and Concha Gil},
  journal={Proteomics},
  year={2014},
  volume={14 12},
  pages={1503-18}
}
In response to different stimuli, macrophages can differentiate into either a pro-inflammatory subtype (M1, classically activated macrophages) or acquire an anti-inflammatory phenotype (M2, alternatively activated macrophages). Candida albicans is the most important opportunistic fungus in nosocomial infections, and it is contended by neutrophils and macrophages during the first steps of the invasive infection. Murine macrophages responses to C. albicans have been widely studied, whereas the… CONTINUE READING
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