Proteomic changes in serum of first onset, antidepressant drug-naïve major depression patients.

  title={Proteomic changes in serum of first onset, antidepressant drug-na{\"i}ve major depression patients.},
  author={Viktoria Stelzhammer and Frieder Haenisch and Man Kwong Chan and Jason. D Cooper and Johann Steiner and Hannah Steeb and Daniel Martins-de-Souza and Hassan Rahmoune and Paul c. Guest and Sabine Bahn},
  journal={The international journal of neuropsychopharmacology},
  volume={17 10},
Major depressive disorder (MDD) is a complex and multi-factorial disorder. Although genetic factors and other molecular aspects of MDD have been widely studied, the underlying pathological mechanisms are still mostly unknown. We sought to investigate the pathophysiology of MDD by identifying and characterising serum molecular differences and their correlation to symptom severity in first onset, antidepressant drug-naïve MDD patients. We performed an exploratory molecular profiling study on… CONTINUE READING
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