Proteomic changes in renal cancer and co‐ordinate demonstration of both the glycolytic and mitochondrial aspects of the Warburg effect

@article{Unwin2003ProteomicCI,
  title={Proteomic changes in renal cancer and co‐ordinate demonstration of both the glycolytic and mitochondrial aspects of the Warburg effect},
  author={Richard D. Unwin and Rachel A. Craven and Patricia Harnden and Sarah Hanrahan and Nicholas F. Totty and Margaret A. Knowles and Ian Eardley and Peter J. Selby and Rosamonde E. Banks},
  journal={PROTEOMICS},
  year={2003},
  volume={3}
}
Renal cell carcinoma (RCC) is the tenth most common cancer although the incidence is increasing. The main clinical problems stem from the relatively late presentation of many patients due to the often asymptomatic nature of the illness, and the relative insensitivity of metastatic disease to conventional chemotherapy and radiotherapy. Despite increasing knowledge of some of the genetic changes underlying sporadic renal cancer such as those involving the Von Hippel Lindau (VHL) gene, many of the… 

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