Proteomic changes in HEK-293 cells induced by hepatitis delta virus replication.

@article{Mendes2013ProteomicCI,
  title={Proteomic changes in HEK-293 cells induced by hepatitis delta virus replication.},
  author={Marta Mendes and Daniel Perez-Hernandez and J. V{\'a}zquez and A. Coelho and C. Cunha},
  journal={Journal of proteomics},
  year={2013},
  volume={89},
  pages={
          24-38
        }
}
UNLABELLED Hepatitis delta virus (HDV) infection greatly increases the risk of hepatocellular carcinoma in hepatitis B virus chronically infected patients. HDV is highly dependent on host factors for accomplishment of the replication cycle. However, these factors are largely unknown and the mechanisms involved in the pathogenicity of the virus still remain elusive. Here, we made use of the HEK-293 cell line, which was engineered in order to mimic HDV replication. Five different proteomes were… Expand
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