Proteomic and genomic characterization of chromatin complexes at a boundary

@article{Tackett2005ProteomicAG,
  title={Proteomic and genomic characterization of chromatin complexes at a boundary},
  author={Alan J. Tackett and David J. Dilworth and Megan J. Davey and Michael E O'Donnell and John D. Aitchison and Michael P. Rout and Brian T Chait},
  journal={The Journal of Cell Biology},
  year={2005},
  volume={169},
  pages={35 - 47}
}
We have dissected specialized assemblies on the Saccharomyces cerevisiae genome that help define and preserve the boundaries that separate silent and active chromatin. These assemblies contain characteristic stretches of DNA that flank particular regions of silent chromatin, as well as five distinctively modified histones and a set of protein complexes. The complexes consist of at least 15 chromatin-associated proteins, including DNA pol epsilon, the Isw2-Itc1 and Top2 chromatin remodeling… CONTINUE READING
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