Proteomic analysis related to stress urinary incontinence following vaginal trauma in female mice.

@article{Chen2013ProteomicAR,
  title={Proteomic analysis related to stress urinary incontinence following vaginal trauma in female mice.},
  author={Huey-Yi Chen and Chao-Jung Chen and Yu-Ning Lin and Yung-Hsiang Chen and Wen-chi Chen and Chuan-Mu Chen},
  journal={European journal of obstetrics, gynecology, and reproductive biology},
  year={2013},
  volume={171 1},
  pages={
          171-9
        }
}
OBJECTIVE The molecular mechanisms underlying stress urinary incontinence (SUI) are not clear. In light of the limited availability of human tissue for study, we explored the changes in the urethra of C57BL/6 mice with experimentally induced SUI. STUDY DESIGN Twelve virgin female mice were randomized into two groups: one group undergoing vaginal distension (VD) for 1h with an 8-mm dilator, and a non-instrumented control group. Four days after VD, leak point pressures (LPP) and maximum… CONTINUE READING
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