Proteomic analysis of the oxidative stress response in Kluyveromyces lactis and effect of glutathione reductase depletion.

@article{GarcaLeiro2010ProteomicAO,
  title={Proteomic analysis of the oxidative stress response in Kluyveromyces lactis and effect of glutathione reductase depletion.},
  author={Ana Garc{\'i}a-Leiro and Mar{\'i}a Esperanza Cerd{\'a}n and Mar{\'i}a Isabel Gonz{\'a}lez-Siso},
  journal={Journal of proteome research},
  year={2010},
  volume={9 5},
  pages={2358-76}
}
Yeasts are unicellular eukaryotes that provide useful models for studying the oxidative stress (OS) response. Most investigations to date have been performed on the fermentative Saccharomyces cerevisiae. The respiratory Kluyveromyces lactis is emerging as an alternative model. Our previous studies showed that glutathione reductase (Glr1) is an interesting point of difference in the OS response between the two yeasts. In the present study, using extensive proteomic analyses, the response to H(2… CONTINUE READING